Ludonin and Carbamazepine a treatment for idiopathie trigeminal neurogia
A comparative study

Idiopathie trigeminal neurogia is the name given to brief paroxgsms of scaring facial pain.It occurs in the edlerly without any accompanying physical signs. The diagnosis criteria in the paper as follows: 1.Paroxgsmal attacks of facial or frontal pain which last a few second to lest than two minutes.2.Pain has at least four of the charrateristies (eg.dis- tribution along one or more divisions of the trigemina nerve, sudden, pain intersity severe, precipitation form trigger areas and between Paroxysms the patient in entirely asgmptoms).3.No neurological deficit.4.Attacks are stereotyped in the individual patient .5.exclusion of other carrses of facial pain.

The thrapic effects of traditional Chinese drug C Ludonin, contain:Bai jiang can,Chuan xiong,Dang gui etc and Carbama- zepine were analgsed.983 patients with idiopathie trigeminal neutogia are summarized.Patients' are from 26-83 years old >=40 years old in 903 cages(91.8%).The courses of the illness were from 2 months to 4.5 years,>=1 years in 892 cases (90.7%).Their pain distribution as follows (table 1)

table 1 Pain distribution

	I	II	III	I II	II III	I II III	total
left	21	68	83	35	101	23	331
right	78	159	136	57	161	61	652
total	99	227	219	92	262	84	983

I...Ophthalmic branch

II ...Maxillary branch

III ...Mandibular branch

The ludonin thrapy was used in 500 cases(50.8%).Carbamazepine thrapy was used in 483 cases(49.1%).Similar sex,year-old and courses of illness in two groups were recorded.Ludonin 50ml,bid,P.O,Carbamazepine 100mg,bid to tid,P.O.These patients were given medicine to continue for one month.The result of treatment as follows(table 2)

Table 2 Result of thrapy

	recovery cases(%)	marked improvement cases(%)	improvement cases(%)	no effect cases(%)	total cases(%)
Ludonin n=500	145(29)	151(30.2)	163(30.6)	41(8.2)	459(91.8)
Carbamazepine n=483	0(0)	25(5.2)	325(67.3)	133(27.5)	350(72.5)

notes:recovery...The attacks were stopped

marked improvement...The attacks obviously were decreased and pain marked improvement

improvement...The attacks were decreased and pain improvement

(X=330.6,P<0.001)

The results of thrapic effects were discussed.Total effective ratio of the Ludonin was in 91.8%.The result that the effect of Ludonin were more higher than traditional Western medicine(Carbamazepine).The effective machinesm of traditional chinese drug are possibly:1.Promote the Circulation of .Qi and blood.Exped Wind and get rid of pain.2.Nourish blood and subdne hyperactirity of liver,remove stasis and prenote netidian.Therefore,the improvement of microcirculations of the trigeminal nerve were obtained.
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